Bђњi was intrigued by how quickly the wound...

Cleveland BЂ "Scientists from Case Western strattera no prescritpion University may be on the way to the inhibition or prevention of HIV entering the body, stopping the bacteria that cause periodontal disease infection of tissues in the mouth and helps wounds heal faster by preventing infection. These future achievements can be made possible by the study agent isolated from the common bacteria of the oral cavity. Scientists led by Dr. Aaron Weinberg, Ph.D., professor and head of the Department of Biological Sciences, dean of academic dental school, look at man as a beta defensinsBЂ "natureBЂ ™ s way of keeping oral bacteria from invading the body and messing with personBЂ ™ s healthBЂ "can be used to create new treatments to block bacteria that enters through the epithelial lining and in the body. The five-year, $ 2. 25000000 National Institutes of Health project continues the work of Dr. Weinberg, who began to ponder the impact of bacteria and healing in the mouth when he was in dental practice. His patients come from wounds in the mouth, which have been or himself by biting the cheek or tongue or burning them to the taste of hot food. BЂњI was intrigued by how quickly the wound healed, despite all the bacteria in the mouth. ItBЂ ™ one of the most polluted places on the body, BЂ "Dr. Weinberg said. Dr. Weinberg began studying the concept as an assistant professor at the Department of Periodontology at the University of Washington in the mid 1990's. There he found a group, are common bacteria in the mouth that induce expression and release hBDs from oral epithelial cells that make up the oral mucosa. HBDs, it turned out, kill bacteria, fungi and viruses. Dr. Weinberg received his research program at Case Western, where his group isolated the agent of the oral bacterium nucleatum Fusobacterium, which promotes expression hBDs. He devised a means, FAD-I for the Fusobacterium nucleatum associated beta-defensin inductor. FAD-I has been shown to induce expression and release hBDs not only from oral epithelial cells, but also from epithelial cells that make up the mucous lining of other parts of the body such as skin, respiratory and gastrointestinal and genitourinary tracks. BЂњIt used to be that these pads are simply barriers and all that microorganisms need to do to cause the disease were to go through barriers. Now it appears that the barrier is alive and responds to challenges BЂ "Dr. Weinberg said. BЂњWe began dissection of agents trying to figure out what in the general body that everyone has in their mouth, which promotes the expression of these proteins. BЂ "

BЂњOur goal is ultimately to be able to protect the lining of the body from microbial problems better than the body does this is by FAD-I to promote expression of defensin molecules in vulnerable areas of the mucosa, BЂ" Dr. Weinberg said. They also found that hBDs, when induced, not only antimicrobial but also promote positive immune response to a specific set of white blood cells. The idea is to promote the expression of its own antibiotics natureBЂ ™ s in places that come in contact with the FAD-I. This may be due to injection treatment in the wall of the vagina womanBЂ ™ and to protect it from infection or the spread of HIV through sexual contact, putting substances in gel or paste, or have the dentist put it in your mouth to prevent periodontal disease or gingivitis, or coatings bandages, so that bruise or cut doesnBЂ ™ t get and heal faster, he said. BЂњWouldnBЂ ™ t it be great if we could promote the expression of its own antibiotics mother NatureBЂ ™ s in vulnerable sites intentionally complex sites of FAD-and thereby protect the sites of microbial problems? BЂ "Dr. Weinberg said. Dr. Weinberg is well known for his work studying periodontal bacteria. .